Endo Hiroki manga
In the panic surrounding a worldwide pandemic which kills 15 percent of the population and cripples many more, a secret organization, the Propater, topples the UN and seizes control of much of the world. A boy and a girl, raised in an abandoned virology research center, immune to the virus, are attacked by the Propater and escape. Based strongly on Gnostic mythology, all major characters are named after gnostic deities, and have analogous roles.
Meguru Takayanagi is trying to find a "practical" fighting method rather than the traditional karate he used to do when he was a kid, enrolling himself in a mixed martial arts gym (The fighter's brew) he started on his road to become a "Shooto" fighter, that's when he will find out his best friend from childhood and the dark secret that surrounds the motivation for revenge. Comedy, fights, slice of life, All rounder Meguru has it all